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NKAP Polyklonaler Antikörper

NKAP Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27437-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using NKAP Polyclonal antibody (27437-1-AP)

    WB analysis using 27437-1-AP (same clone as 27437-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27437-1-AP (NKAP antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27437-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27437-1-PBS bindet in WB, Indirect ELISA NKAP und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen NKAP fusion protein Ag26637
Vollständiger Name NFKB activating protein
Berechnetes Molekulargewicht 415 aa, 47 kDa
Beobachtetes Molekulargewicht47-50 kDa
GenBank-ZugangsnummerBC015354
Gene symbol NKAP
Gene ID (NCBI) 79576
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NKAP is a multifunctional nuclear protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. NKAP is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.