CD314/NKG2D Monoklonaler Antikörper

CD314/NKG2D Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG1, kappa

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

CX5

Kat-Nr. : 65100-1-Ig

Synonyme

D6H12S2489E, Klrk1, NKG2 D, Nkg2d, NKG2D (CD314)

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  FC experiment of C57 mouse splenic NK cells using 65100-1-Ig

  1X10^6 C57 mouse splenic NK cells were surface co-stained with FITC Anti-Mouse CD49b and 0.5 ug Anti-Mouse CD314/NKG2D (65100-1-Ig, Clone: CX5) or unstained (blank control). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: C57 mouse splenic NK cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65100-1-Ig bindet in FC CD314/NKG2D und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Ratte / IgG1, kappa
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Purified Mouse NKG2D protein
• Vollständiger Name: killer cell lectin-like receptor subfamily K, member 1
• GenBank-Zugangsnummer: BC057147
• Gene symbol: CD314
• Gene ID (NCBI): 27007
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

CD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In mice, CD314 is expressed on NK cells, activated CD8(+) T cells and macrophages, and subsets of TCR gamma delta (+) and NK1.1 (+) T cells (PMID: 12150888). Various subfamilies of MHC class I-related glycoproteins have been identified as the ligands for mouse CD314, including RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1 (PMID: 31720075).