NKG7 Polyklonaler Antikörper

NKG7 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11532-1-PBS

Synonyme

G CSF induced gene 1 protein, G-CSF-induced gene 1 protein, GIG 1 protein, GIG1, GIG-1 protein

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  WB analysis using 11532-1-AP (same clone as 11532-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11532-1-AP (NKG7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11532-1-PBS in a different storage buffer formulation.

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  IP experiment of NK-92 using 11532-1-AP (same clone as 11532-1-PBS)

  IP result of anti-NKG7 (IP:11532-1-AP, 4ug; Detection:11532-1-AP 1:1000) with NK-92 cells lysate 1120 ug. This data was developed using the same antibody clone with 11532-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 11532-1-AP (same clone as 11532-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 11532-1-AP (NKG7 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11532-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

11532-1-PBS bindet in WB, IHC, IP, Indirect ELISA NKG7 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: NKG7 fusion protein Ag2117
• Vollständiger Name: natural killer cell group 7 sequence
• Berechnetes Molekulargewicht: 165 aa, 18 kDa
• Beobachtetes Molekulargewicht: 18 kDa
• GenBank-Zugangsnummer: BC015759
• Gene symbol: NKG7
• Gene ID (NCBI): 4818
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Natural killer cell granule protein 7 (NKG7) regulates lymphocyte granule exocytosis and downstream inflammation in a broad range of diseases. NKG7 expressed by CD4+ and CD8+ T cells were key in promoting inflammation during visceral leishmaniasis and malaria-two important parasitic diseases. It is expressed by natural killer cells and is critical for controlling cancer initiation, growth, and metastasis (PMID: 32839608; 8458737). In brief, NKG7 is a necessary T-cell intrinsic factor for the cytotoxic function of CD8+ T cells and established NKG7 as a new therapeutic target for cancer immunotherapy (PMID: 34911739).