NKp46/NCR1 Rekombinanter Antikörper

NKp46/NCR1 Rekombinant Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

29A1.4

Kat-Nr. : 65667-1-PBS

Synonyme

Ncr1, Activating receptor 1, CD335, Ly94, Lymphocyte antigen 94

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  FC experiment of mouse splenocytes using 65667-1-TR (same clone as 65667-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse CD335 (29A1.4) Rat IgG2a RecAb (65667-1-TR, Clone:29A1.4) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1), and FITC anti-Rat IgG2a antibody. Cells were then stained with CoraLite® Plus 647 Anti-Mouse CD49b (HMA2) (CL647-65245, Clone: HMA2). Cells were not fixed. This data was developed using the same antibody clone with 65667-1-PBS in a different storage buffer formulation.

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  FC experiment of mouse splenocytes using 65667-1-TR (same clone as 65667-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse CD335 (29A1.4) Rat IgG2a RecAb (65667-1-TR, Clone: 29A1.4) (red) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1) (blue), and FITC anti-Rat IgG2a antibody. Cells were not fixed. This data was developed using the same antibody clone with 65667-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

65667-1-PBS bindet in FC NKp46/NCR1 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Ratte / IgG2a
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: natural cytotoxicity triggering receptor 1
• GenBank-Zugangsnummer: BC042788
• Gene symbol: NKp46/NCR1
• Gene ID (NCBI): 17086
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals (PMID: 22021440). NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail (PMID: 9730896). It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells (PMID: 9730896; 22021440). NKp46 is the major triggering receptor involved in the natural cytotoxicity (PMID: 10359120; 10092106; 15356098).