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NMDAR2B/GRIN2B Monoklonaler Antikörper

NMDAR2B/GRIN2B Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1C5E12

Kat-Nr. : 66565-1-PBS

Synonyme

GluN2B, GRIN2B, hNR3, NMDAR2B, NMDAR2B/GRIN2B, NR2B, NR3

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using NMDAR2B/GRIN2B Monoclonal antibody (66565-1-Ig)

    WB analysis of mouse brain using 66565-1-Ig (same clone as 66565-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 66565-1-Ig (NMDAR2B/GRIN2B antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66565-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of rat brain tissue using NMDAR2B/GRIN2B Monoclonal antibody (66565-1-Ig)

    WB analysis of rat brain using 66565-1-Ig (same clone as 66565-1-PBS)

    rat brain tissue were subjected to SDS PAGE followed by western blot with 66565-1-Ig (NMDAR2B/GRIN2B antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66565-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66565-1-PBS bindet in WB, Indirect ELISA NMDAR2B/GRIN2B und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen NMDAR2B/GRIN2B fusion protein Ag16718
Vollständiger Name glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Berechnetes Molekulargewicht 1484 aa, 166 kDa
Beobachtetes Molekulargewicht 166 kDa
GenBank-ZugangsnummerBC113620
Gene symbol GRIN2B
Gene ID (NCBI) 2904
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GRIN2B (also known as GluN2B or NMDAR2B) is a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. NMDA receptors are widely expressed in the central nervous system and play a major role in excitatory synaptic transmission and plasticity (PMID: 23223336). NMDA receptors large multi-subunit complexes arranged into heteromeric assemblies composed of four homologous subunits within a repertoire of over 10 different subunits: eight GluN1 isoforms, four GluN2 subunits (A-D) and two GluN3 subunits (A and B) (PMID: 21395862). Naturally occurring mutations within GRIN2B gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia.