NONO Monoklonaler Antikörper

NONO Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2A2B10

Kat-Nr. : 66361-1-PBS

Synonyme

2A2B10, 54 kDa nuclear RNA- and DNA-binding protein, 55 kDa nuclear protein, NonO protein, Non-POU domain-containing octamer-binding protein

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  WB analysis of C2C12 using 66361-1-Ig (same clone as 66361-1-PBS)

  C2C12 cell were subjected to SDS PAGE followed by western blot with 66361-1-Ig (NONO Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66361-1-PBS in a different storage buffer formulation.

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  WB analysis of ROS1728 using 66361-1-Ig (same clone as 66361-1-PBS)

  ROS1728 cells were subjected to SDS PAGE followed by western blot with 66361-1-Ig (NONO Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66361-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse skeletal muscle using 66361-1-Ig (same clone as 66361-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 66361-1-Ig (NONO Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66361-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66361-1-PBS bindet in WB, Indirect ELISA NONO und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: NONO fusion protein Ag17609
• Vollständiger Name: non-POU domain containing, octamer-binding
• Berechnetes Molekulargewicht: 54 kDa
• Beobachtetes Molekulargewicht: 54 kDa
• GenBank-Zugangsnummer: BC010049
• Gene symbol: NONO
• Gene ID (NCBI): 4841
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Non-pou domain-containing octamer-binding protein(NONO), other named p54nrb, belongs to DBHS family, whose protein are predominately nuclear and involves in transcriptional and posttranscriptional gene regulatory functions as well as DNA repair. This family has roles in a wide range of biological processes, such as the regulation of circadian rhythm, carcinogenesis and progression of cancer. NONO forms heterodimer with SFPQ, and has been implicated in nuclear retention of A- to I-edited RNA as paraspeckle components, pre-mRAN 3'-end formation, cAMP cycling and transcriptional activation.