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- KD/KO Validated
NONO Polyklonaler Antikörper
NONO Polyklonal Antikörper für
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
Konjugation
CoraLite® Plus 647 Fluorescent Dye
Kat-Nr. : CL647-11058
Synonyme
Geprüfte Anwendungen
Produktinformation
CL647-11058 bindet in NONO und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | NONO fusion protein Ag1512 |
| Vollständiger Name | non-POU domain containing, octamer-binding |
| Berechnetes Molekulargewicht | 54 kDa |
| Beobachtetes Molekulargewicht | 54 kDa |
| GenBank-Zugangsnummer | BC010049 |
| Gene symbol | NONO |
| Gene ID (NCBI) | 4841 |
| Konjugation | CoraLite® Plus 647 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 654 nm / 674 nm |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA |
| Lagerungsbedingungen | Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Non-pou domain-containing octamer-binding protein(NONO), other named p54nrb, belongs to DBHS family, whose protein are predominately nuclear and involves in transcriptional and posttranscriptional gene regulatory functions as well as DNA repair. This family has roles in a wide range of biological processes, such as the regulation of circadian rhythm, carcinogenesis and progression of cancer. NONO forms heterodimer with SFPQ, and has been implicated in nuclear retention of A- to I-edited RNA as paraspeckle components, pre-mRAN 3'-end formation, cAMP cycling and transcriptional activation.
