• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

NOTCH4 Polyklonaler Antikörper

NOTCH4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33280-1-PBS

Synonyme

hNotch4, INT3, Notch 4, Notch 4 extracellular truncation, Notch 4 intracellular domain

Filter:
  • Western Blot (WB) analysis of various lysates using NOTCH4 Polyclonal antibody (33280-1-AP)

    WB analysis using 33280-1-AP (same clone as 33280-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33280-1-AP (NOTCH4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33280-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33280-1-PBS bindet in WB, Indirect ELISA NOTCH4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen NOTCH4 fusion protein Ag36738
Vollständiger Name Notch homolog 4 (Drosophila)
Berechnetes Molekulargewicht 2003 aa, 210 kDa
Beobachtetes Molekulargewicht210 kDa
GenBank-ZugangsnummerBC140782
Gene symbol NOTCH4
Gene ID (NCBI) 4855
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Neurogenic locus notch homolog protein 4 (NOTCH4) is a receptor involved in the Notch signaling pathway, which is synthesized as a precursor that undergoes proteolytic cleavage to form an active receptor. NOTCH4 interacts with various ligands, leading to the release of the Notch intracellular domain (NICD), which translocates to the nucleus and regulates gene expression (PMID: 28794168; 19379690; 17148788). NOTCH4 is involved in various biological processes, including embryonic development, immune cell differentiation, and tumorigenesis (PMID: 24667410; 34925319).