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NPR2 Polyklonaler Antikörper

NPR2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55113-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of transfected cells using NPR2 Polyclonal antibody (55113-1-AP)

    WB analysis of transfected cells using 55113-1-AP (same clone as 55113-1-PBS)

    WB result of anti-NPR2 (55113-1-AP, 1:1000) with HEK293 overexpressed NPR2 by Jeremy Egbert and Laurinda Jaffe. (Another anti serum 6328 as control). This data was developed using the same antibody clone with 55113-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55113-1-PBS bindet in WB, Indirect ELISA NPR2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
Berechnetes Molekulargewicht 117 kDa
Beobachtetes Molekulargewicht 111 kDa, 117 kDa
GenBank-ZugangsnummerNM_003995
Gene symbol NPR2
Gene ID (NCBI) 4882
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NPR2, also named as ANPRB, GC-B, NPR-B, ANPR-B and ANP-B, belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It is a receptor for the C-type natriuretic peptide NPPC/CNP hormone. NRP2 has guanylate cyclase activity upon binding of its ligand. It may play a role in the regulation of skeletal growth. NPR2 is the primary receptor for C type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Defects in NPR2 are the cause of acromesomelic dysplasia Maroteaux type (AMDM). The antibody is specific to NPR2.