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NPTX2 Polyklonaler Antikörper
NPTX2 Polyklonal Antikörper für WB, IHC, IF/ICC, IP, ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, IF/ICC, IP, ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 10889-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
10889-1-PBS bindet in WB, IHC, IF/ICC, IP, ELISA NPTX2 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte | 
| Wirt / Isotyp | Kaninchen / IgG | 
| Klonalität | Polyklonal | 
| Typ | Antikörper | 
| Immunogen | NPTX2 fusion protein Ag1326 | 
| Vollständiger Name | neuronal pentraxin II | 
| Berechnetes Molekulargewicht | 47 kDa | 
| Beobachtetes Molekulargewicht | 47-50 kDa | 
| GenBank-Zugangsnummer | BC009924 | 
| Gene symbol | NPTX2 | 
| Gene ID (NCBI) | 4885 | 
| Konjugation | Unkonjugiert | 
| Form | Liquid | 
| Reinigungsmethode | Antigen-Affinitätsreinigung | 
| Lagerungspuffer | PBS only | 
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. | 
Hintergrundinformationen
Neuronal pentraxins constitute a family of proteins that are homologous to C-reactive protein (CRP) and serum amyloid P component (SAP), including NPTX1, NPTX2, and the neuronal pentraxin receptor (NPTXR). NPTX2, also known as NARP (neuronal activity-regulated pentaxin), is a secreted protein involved in excitatory synapse formation. It also plays a role in the clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. NPTX2 is highly up-regulated in Parkinson's disease (PD), suggesting it may be involved in the pathology of PD. (PMID: 12895424; 17987278; 10748068)



















