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NPTX2 Monoklonaler Antikörper

NPTX2 Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Kaninchen, Maus, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2H8D8

Kat-Nr. : 68709-1-PBS

Synonyme

2H8D8, Neuronal pentraxin II, Neuronal pentraxin-2, NP2, NP-II

Filter:
  • Western Blot (WB) analysis of various lysates using NPTX2 Monoclonal antibody (68709-1-Ig)

    WB analysis using 68709-1-Ig (same clone as 68709-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68709-1-Ig (NPTX2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68709-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of SH-SY5Y cells using NPTX2 Monoclonal antibody (68709-1-Ig)

    IF Staining of SH-SY5Y using 68709-1-Ig (same clone as 68709-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using NPTX2 antibody (68709-1-Ig, Clone: 2H8D8 ) at dilution of 1:800 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 68709-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68709-1-PBS bindet in WB, IF/ICC, Indirect ELISA NPTX2 und zeigt Reaktivität mit Hausschwein, human, Kaninchen, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Kaninchen, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen NPTX2 fusion protein Ag33808
Vollständiger Name neuronal pentraxin II
Berechnetes Molekulargewicht 47 kDa
Beobachtetes Molekulargewicht50-55 kDa
GenBank-ZugangsnummerBC009924
Gene symbol NPTX2
Gene ID (NCBI) 4885
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Neuronal pentraxins constitute a family of proteins that are homologous to C-reactive protein (CRP) and serum amyloid P component (SAP), including NPTX1, NPTX2, and the neuronal pentraxin receptor (NPTXR). NPTX2, also known as NARP (neuronal activity-regulated pentaxin), is a secreted protein involved in excitatory synapse formation. It also plays a role in the clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. NPTX2 is highly up-regulated in Parkinson's disease (PD), suggesting it may be involved in the pathology of PD. (PMID: 12895424; 17987278; 10748068)