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NR1H2 Monoklonaler Antikörper

NR1H2 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

1E12B10

Kat-Nr. : 60345-1-PBS

Synonyme

1E12B10, Liver X receptor beta, LXR b, LXRB, NER

Filter:
  • Western Blot (WB) analysis of human liver tissue using NR1H2 Monoclonal antibody (60345-1-Ig)

    WB analysis of human liver using 60345-1-Ig (same clone as 60345-1-PBS)

    human liver tissue were subjected to SDS PAGE followed by western blot with 60345-1-Ig (NR1H2 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60345-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of pig liver tissue using NR1H2 Monoclonal antibody (60345-1-Ig)

    WB analysis of pig liver using 60345-1-Ig (same clone as 60345-1-PBS)

    pig liver tissue were subjected to SDS PAGE followed by western blot with 60345-1-Ig (NR1H2 Antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60345-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

60345-1-PBS bindet in WB, ELISA NR1H2 und zeigt Reaktivität mit Hausschwein, human

Getestete Reaktivität Hausschwein, human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen NR1H2 fusion protein Ag5635
Vollständiger Name nuclear receptor subfamily 1, group H, member 2
Berechnetes Molekulargewicht 51 kDa
Beobachtetes Molekulargewicht 51 kDa
GenBank-ZugangsnummerBC047750
Gene symbol NR1H2
Gene ID (NCBI) 7376
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NR1H2, also known as LXRB, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. It preferentially bind to double-stranded oligonucleotide direct repeats, which have the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). It involves in the regulation of cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.