NR1H3 Monoklonaler Antikörper

NR1H3 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

4A4F7

Kat-Nr. : 60134-1-PBS

Synonyme

Oxysterols receptor LXR alpha, LXRα, LXRA, LXR a, Liver X receptor alpha

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  WB analysis using 60134-1-Ig (same clone as 60134-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60134-1-Ig (NR1H3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60134-1-PBS in a different storage buffer formulation.

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  WB analysis of MCF-7 using 60134-1-Ig (same clone as 60134-1-PBS)

  MCF7 cells were subjected to SDS PAGE followed by western blot with 60134-1-Ig (NR1H3 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60134-1-PBS in a different storage buffer formulation.

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  WB analysis of HepG2 using 60134-1-Ig (same clone as 60134-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 60134-1-Ig (NR1H3 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60134-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

60134-1-PBS bindet in WB, Indirect ELISA NR1H3 und zeigt Reaktivität mit Hausschwein, human, Ratten

• Getestete Reaktivität: Hausschwein, human, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: NR1H3 fusion protein Ag6184
• Vollständiger Name: nuclear receptor subfamily 1, group H, member 3
• Berechnetes Molekulargewicht: 50 kDa
• Beobachtetes Molekulargewicht: 44 kDa
• GenBank-Zugangsnummer: BC041172
• Gene symbol: NR1H3
• Gene ID (NCBI): 10062
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements.