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NR2F6 Rekombinanter Antikörper

NR2F6 Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251076E2

Kat-Nr. : 86371-1-PBS

Synonyme

EAR 2, EAR2, EAR-2, ERBAL2, V erbA related protein 2

Filter:
  • Western Blot (WB) analysis of various lysates using NR2F6 Recombinant antibody (86371-1-RR)

    WB analysis using 86371-1-RR (same clone as 86371-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86371-1-RR (NR2F6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86371-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using NR2F6 Recombinant antibody (86371-1-RR)

    IF Staining of U2OS using 86371-1-RR (same clone as 86371-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using NR2F6 antibody (86371-1-RR, Clone: 251076E2 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 86371-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using NR2F6 Recombinant antibody (86371-1-RR)

    IF Staining of HeLa using 86371-1-RR (same clone as 86371-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using NR2F6 antibody (86371-1-RR, Clone: 251076E2 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 86371-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86371-1-PBS bindet in WB, IF/ICC, Indirect ELISA NR2F6 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen NR2F6 fusion protein Ag7614
Vollständiger Name nuclear receptor subfamily 2, group F, member 6
Berechnetes Molekulargewicht 43 kDa
Beobachtetes Molekulargewicht40-43 kDa
GenBank-ZugangsnummerBC002669
Gene symbol NR2F6
Gene ID (NCBI) 2063
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NR2F6 belongs to NR2F subfamily members, which have their roles in the regulation of neurogenesis, organogenesis, and cellular differentiation during embryonic development (PMID:15875024). NR2F6 acts as transcription factor by binding to a TGACCT direct-repeat motif and has been established in controlling facets of central nervous system (CNS) (PMID: 12690040). It is a nuclear attenuator that directly interferes with DNA binding of NF-AT and, subsequently, transcriptional activity of the NF-AT-dependent IL-17 expression. Otherwise, NR2F6 negatively interfered with transcriptional cytokine responses and acted as a barrier against autoimmunity (PMID:18701084).