• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
  • Featured Product
  • KD/KO Validated

NR5A2 Polyklonaler Antikörper

NR5A2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22460-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using NR5A2 Polyclonal antibody (22460-1-AP)

    WB analysis using 22460-1-AP (same clone as 22460-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22460-1-AP (NR5A2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22460-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse ovary tissue using NR5A2 Polyclonal antibody (22460-1-AP)

    WB analysis of mouse ovary using 22460-1-AP (same clone as 22460-1-PBS)

    mouse ovary tissue were subjected to SDS PAGE followed by western blot with 22460-1-AP (NR5A2 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22460-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of rat testis tissue using NR5A2 Polyclonal antibody (22460-1-AP)

    WB analysis of rat testis using 22460-1-AP (same clone as 22460-1-PBS)

    rat testis tissue were subjected to SDS PAGE followed by western blot with 22460-1-AP (NR5A2 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22460-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22460-1-PBS bindet in WB, Indirect ELISA NR5A2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen NR5A2 fusion protein Ag18001
Vollständiger Name nuclear receptor subfamily 5, group A, member 2
Berechnetes Molekulargewicht 541 aa, 61 kDa
Beobachtetes Molekulargewicht 61-67 kDa
GenBank-ZugangsnummerBC118652
Gene symbol NR5A2
Gene ID (NCBI) 2494
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-affinitätsgereinigt
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NR5A2 belongs to the nuclear hormone receptor family NR5 subfamily.It binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation.NR5A2 may be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development. LRH-1 is phosphorylated to display its normal function, including its role in the intriguing potential responses to phospholipid or other ligands. The hinge domain serine residues at 238 and 243 are required for effective phosphorylation, both in vitro and in cells (16439367).NR5A1 is abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in hepG2. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and hepG2 cells.The observed molecular weight of 65-70 kDa is the posphorylation of NR5A2 protein.