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NRAMP1 Polyklonaler Antikörper

NRAMP1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32308-1-PBS

Synonyme

SLC11A1, NRAMP 1

Filter:
  • Western Blot (WB) analysis of various lysates using NRAMP1 Polyclonal antibody (32308-1-AP)

    WB analysis using 32308-1-AP (same clone as 32308-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32308-1-AP (NRAMP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32308-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using NRAMP1 Polyclonal antibody (32308-1-AP)

    WB analysis using 32308-1-AP (same clone as 32308-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32308-1-AP (NRAMP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32308-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32308-1-PBS bindet in WB, Indirect ELISA NRAMP1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Berechnetes Molekulargewicht 432 aa, 48 kDa
Beobachtetes Molekulargewicht 60 kDa
GenBank-ZugangsnummerBC071165
Gene symbol SLC11A1
Gene ID (NCBI) 6556
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC11A1 also known as NRAMP1, belongs to the SLC11 family of solute carriers, which mediate the transport of divalent metals. NRAMP1 is a divalent metal importer specifically expressed in the membranes of late endosomes/lysosomes of professional phagocytes. It plays a crucial role in the defense against intracellular pathogens by depleting essential metal ions from endocytosed microbes, thereby preventing their proliferation(PMID: 24832660, PMID: 39824808).