NRD1 Polyklonaler Antikörper

NRD1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15630-1-PBS

Synonyme

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  WB analysis using 15630-1-AP (same clone as 15630-1-PBS)

  K-562 cells lysates were subjected to SDS PAGE followed by western blot with 15630-1-AP (NRD1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15630-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 15630-1-AP (same clone as 15630-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 15630-1-AP (NRD1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15630-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 15630-1-AP (same clone as 15630-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 15630-1-AP (NRD1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 15630-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

15630-1-PBS bindet in WB, IHC, Indirect ELISA NRD1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: NRD1 fusion protein Ag7923
• Vollständiger Name: nardilysin (N-arginine dibasic convertase)
• Berechnetes Molekulargewicht: 132 kDa
• Beobachtetes Molekulargewicht: 135-140 kDa
• GenBank-Zugangsnummer: BC008775
• Gene symbol: NRD1
• Gene ID (NCBI): 4898
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NRD1(Nardilysin) is also named as NRD-C(N-arginine dibasic convertase). It is a zinc metalloendopeptidase of the M16 pitrilysin family that cleaves peptides at dibasic residues. The enzyme has also been found in neural tissues of mouse embryos indicating a role in neural development. Although nardilysin is primarily found in the cytosol, it has been reported that nardilysin is located on the cell surface acting as a receptor for heparinbinding EGF-like growth factor(PMID:15809022). It has 2 isoforms produced by alternative splicing.