NRG1, isoform Alpha Rekombinanter Antikörper

NRG1, isoform Alpha Rekombinant Antikörper für IF/ICC, IF-P, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, IF-P, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240067A6

Kat-Nr. : 83251-2-PBS

Synonyme

NRG1, NRG1A, 240067A6, ARIA, GGF

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  IF Staining of rat brain using 83251-2-RR (same clone as 83251-2-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat brain tissue using NRG1, isoform Alpha antibody (83251-2-RR, Clone: 240067A6 ) at dilution of 1:500 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83251-2-PBS in a different storage buffer formulation.

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  IF Staining of MCF-7 using 83251-2-RR (same clone as 83251-2-PBS)

  Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using NRG1, isoform Alpha antibody (83251-2-RR, Clone: 240067A6 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83251-2-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83251-2-PBS

  Biolayer interferometry (BLl) kinetic assay of 83251-2-PBS against Human NRG1, isoform Alpha was performed. The affinity constant is 16.9 nM.

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Geprüfte Anwendungen

Produktinformation

83251-2-PBS bindet in IF/ICC, IF-P, Cytometric bead array, Indirect ELISA NRG1, isoform Alpha und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: NRG1, isoform Alpha fusion protein Ag35114
• Vollständiger Name: neuregulin 1
• Berechnetes Molekulargewicht: 70 kDa
• Beobachtetes Molekulargewicht: 70 kDa
• GenBank-Zugangsnummer: BC007675
• Gene symbol: NRG1
• Gene ID (NCBI): 3084
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Neuregulin 1 (NRG1) is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by usage of different promoters and alternative splicing of a single gene. NRG1 and its receptor ErbB tyrosine kinase are expressed not only in the developing nervous system, but also in the adult brain. The immunogen of this antibody is against NRG1 isoform Alpha.