NRG4 Polyklonaler Antikörper

NRG4 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27292-1-PBS

Synonyme

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  WB analysis using 27292-1-AP (same clone as 27292-1-PBS)

  Recombinant human NRG4 protein Eg0997 was subjected to SDS PAGE followed by western blot with 27292-1-AP (NRG4 antibody) at dilution of 1:3000 and incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 27292-1-AP (same clone as 27292-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 27292-1-AP (NRG4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 27292-1-AP (same clone as 27292-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 27292-1-AP (NRG4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 27292-1-AP (same clone as 27292-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27292-1-AP (NRG4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 27292-1-AP (same clone as 27292-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27292-1-AP (NRG4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

27292-1-PBS bindet in IHC, Indirect ELISA NRG4 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: NRG4 fusion protein Ag26044
• Vollständiger Name: neuregulin 4
• Berechnetes Molekulargewicht: 13 kDa
• GenBank-Zugangsnummer: BC017568
• Gene symbol: NRG4
• Gene ID (NCBI): 145957
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Neuregulin 4 (Nrg4), a member of the epidermal growth factor (EGF) family of extracellular ligands, is expressed in multiple organs with the highest expression levels in brown adipose tissue. Neuregulin 4 is a secreted adipokine recently identified as playing an important role in modulating systemic energy metabolism and in the development of metabolic disorders in rodent and human obesity, including type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Nrg4 attenuates hepatic lipogenic signaling and preserves glucose and lipid homeostasis in obesity.