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NTN3 Polyklonaler Antikörper

NTN3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31893-1-PBS

Synonyme

NTN2L, Netrin-3, Netrin-2-like protein, netrin 3, Netrin 2 like protein

Filter:
  • Western Blot (WB) analysis of various lysates using NTN3 Polyclonal antibody (31893-1-AP)

    WB analysis using 31893-1-AP (same clone as 31893-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31893-1-AP (NTN3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31893-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31893-1-PBS bindet in WB, Indirect ELISA NTN3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen NTN3 fusion protein Ag34435
Vollständiger Name netrin 3
Berechnetes Molekulargewicht61 kDa
Beobachtetes Molekulargewicht62-70 kDa
GenBank-ZugangsnummerNetrin-3
Gene symbol NTN3
Gene ID (NCBI) 4917
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NTN3 (Netrin-3), also known as NTN2L. NTN3 (Netrin-3) is predicted to be located in the Golgi apparatus and extracellular region, and it is also predicted to be active in the basement membrane. It is detected in various amounts in the skin, esophagus, bronchus, nasal cavity, kidney, and vagina in healthy human tissues (PMID: 37345154). The protein is predicted to enable signaling receptor binding activity and is involved in animal organ morphogenesis, neuron projection development, and tissue development. Netrins, including NTN3, are a group of proteins that exhibit structural homology to the extracellular matrix protein laminin and influence neurological and tumor progression. NTN3, along with other netrin family members, may play a role in tumor growth and migration in specific organs where they are expressed, potentially affecting disease progression. However, further research is needed to elucidate the precise prognostic and biological implications of NTN3 in various diseases, including cancer (PMID: 32251318). The molecular weight of NTN3 is 62 kDa. It is possible that the protein has glycosylation modification.