TrkA Monoklonaler Antikörper

TrkA Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3B11C7

Kat-Nr. : 60548-1-PBS

Synonyme

NTRK1, Trk A, TRK, p140 TrkA, MTC

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  WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

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  WB analysis of NK-92 using 60548-1-Ig (same clone as 60548-1-PBS)

  NK-92 cells were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

60548-1-PBS bindet in WB, Indirect ELISA TrkA und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: TrkA fusion protein Ag27985
• Vollständiger Name: neurotrophic tyrosine kinase, receptor, type 1
• Berechnetes Molekulargewicht: 88 kDa
• Beobachtetes Molekulargewicht: 140 kDa
• GenBank-Zugangsnummer: NM_001007792
• Gene symbol: NTRK1
• Gene ID (NCBI): 4914
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NTRK1(Neurotrophic tyrosine kinase receptor 1) is located on chromosome 1q23.1 and is responsible for a rare genetic disorder, CIPA (congenital insensitivity to pain with anhidrosis) (PMID: 37907480). As a neurotrophin receptor, NTRK1 is abundantly expressed in human neuronal tissues and plays an integral role in the development and function of the human nervous system (PMID: 27843590). NTRK1 also regulates the survival and proliferation of cholinergic neurons (PMID: 20054812).