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TrkA Rekombinanter Antikörper

TrkA Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240440D12

Kat-Nr. : 83477-7-PBS

Synonyme

NTRK1, Trk A, TRK, p140 TrkA, MTC

Filter:
  • Western Blot (WB) analysis of K-562 cells using TrkA Recombinant antibody (83477-7-RR)

    WB analysis of K-562 using 83477-7-RR (same clone as 83477-7-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 83477-7-RR (TrkA antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83477-7-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of SH-SY5Y cells using TrkA Recombinant antibody (83477-7-RR)

    WB analysis of SH-SY5Y using 83477-7-RR (same clone as 83477-7-PBS)

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 83477-7-RR (TrkA antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83477-7-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83477-7-RR

    Affinity and Kinetic Characterization of 83477-7-RR

    Biolayer interferometry (BLl) kinetic assays of 83477-7-RR against Human NTRK1 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

83477-7-PBS bindet in WB, ELISA TrkA und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TrkA fusion protein Ag32759
Vollständiger Name neurotrophic tyrosine kinase, receptor, type 1
Berechnetes Molekulargewicht88 kDa
Beobachtetes Molekulargewicht140 kDa
GenBank-ZugangsnummerNM_001007792
Gene symbol NTRK1
Gene ID (NCBI) 4914
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NTRK1(Neurotrophic tyrosine kinase receptor 1) is located on chromosome 1q23.1 and is responsible for a rare genetic disorder, CIPA (congenital insensitivity to pain with anhidrosis) (PMID: 37907480). As a neurotrophin receptor, NTRK1 is abundantly expressed in human neuronal tissues and plays an integral role in the development and function of the human nervous system (PMID: 27843590). NTRK1 also regulates the survival and proliferation of cholinergic neurons (PMID: 20054812).