TrkC Polyklonaler Antikörper

TrkC Polyklonal Antikörper für WB, IHC, IF/ICC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, ELISA

Konjugation

Unkonjugiert

Publikationen(4)

Kat-Nr. : 11999-1-AP

Synonyme

NTRK3, EC:2.7.10.1, GP145 TrkC, gp145(trkC), GP145-TrkC

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  WB analysis of fetal human brain using 11999-1-AP

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 11999-1-AP (TrkC antibody at dilution of 1:300 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse brain using 11999-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 11999-1-AP (TrkC antibody at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of rat brain using 11999-1-AP

  rat brain tissue were subjected to SDS PAGE followed by western blot with 11999-1-AP (TrkC antibody at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  IHC staining of human brain using 11999-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 11999-1-AP (TrkC antibody at dilution of 1:200 (under 10x lens).

• 

  IHC staining of human brain using 11999-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 11999-1-AP (TrkC antibody at dilution of 1:200 (under 40x lens).

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  IF Staining of A549 using 11999-1-AP

  Immunofluorescent analysis of (-20℃ Ethanol) fixed A549 cells using 11999-1-AP (TrkC antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: fetales humanes Hirngewebe, Maushirngewebe, Rattenhirngewebe
• Erfolgreiche Detektion in IHC: humanes Hirngewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.
• Erfolgreiche Detektion in IF/ICC: A549-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:200-1:1000
• Immunhistochemie (IHC): IHC : 1:50-1:500
• Immunfluoreszenz (IF)/ICC: IF/ICC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 4 publications below

Produktinformation

11999-1-AP bindet in WB, IHC, IF/ICC, ELISA TrkC und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TrkC fusion protein Ag2635
• Vollständiger Name: neurotrophic tyrosine kinase, receptor, type 3
• Berechnetes Molekulargewicht: 839 aa, 94 kDa
• Beobachtetes Molekulargewicht: 94 kDa
• GenBank-Zugangsnummer: BC013693
• Gene symbol: TrkC
• Gene ID (NCBI): 4916
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TrkC (Tropomyosin Receptor Kinase C), also known as NTRK3 (Neurotrophic Tyrosine Kinase Receptor Type 3), belongs to the Trk family of receptor tyrosine kinases, which also includes TrkA and TrkB. These receptors are primarily involved in the development and function of the nervous system.

Publikationen

Species	Application	Title
human	WB	Front Cell Dev Biol; Identification of New miRNA-mRNA Networks in the Development of Non-syndromic Cleft Lip With or Without Cleft Palate.; Authors - Chengyi Fu
human	WB	Stem Cell Res Ther; NT3P75-2 gene-modified bone mesenchymal stem cells improve neurological function recovery in mouse TBI model.; Authors - Ke Wu
mouse	WB	iScience; Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice.; Authors - Xiaoju Xu
rat	WB	Transl Androl Urol; Whole body vibration training promotes proprioceptive pathway for the treatment of stress urinary incontinence in rats; Authors - Chengyu Zhou