NUAK2 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

NUAK2 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(4)

Kat-Nr. : 11592-1-AP

Synonyme

SNARK, OMPHK2, NUAK family SNF1-like kinase 2, NUAK 2, EC:2.7.11.1

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Geprüfte Anwendungen

Veröffentlichte Anwendungen

• KD/KO: See 2 publications below
• WB: See 4 publications below
• IHC: See 1 publications below
• IF: See 2 publications below

Produktinformation

11592-1-AP bindet in WB, IHC, IF, ELISA NUAK2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: NUAK2 fusion protein Ag2031
• Vollständiger Name: NUAK family, SNF1-like kinase, 2
• Berechnetes Molekulargewicht: 628 aa, 70 kDa
• Beobachtetes Molekulargewicht: 70 kDa
• GenBank-Zugangsnummer: BC017306
• Gene symbol: NUAK2
• Gene ID (NCBI): 81788
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NUAK2(NUAK family SNF1-like kinase 2) is also named as OMPHK2, SNARK and belongs to the SNF1 subfamily. The function of NUAK2 is partly dependent on anti-apoptotic properties against apoptosis induced by death ligand and NUAK2 also has effects on the migration of cancer cells as speculated from studies on myosin filaments and cytoskeleton organization in normal cells(PMID:21911917). Western blot analysis detected NUAK2 expressed in cancer cell lines of diverse tissue origin(PMID:12409306).

Publikationen

Species	Application	Title
human	WB,IHC	Proc Natl Acad Sci U S A; AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma.; Authors - Namiki Takeshi T
human	WB, IF	Cancer Res; NUAK2 amplification coupled with PTEN deficiency promote melanoma development via CDK activation.; Authors - Takeshi Namiki ; KD Validated
human	WB	Diabetologia; Regulation of skeletal muscle sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) by metabolic stress and diabetes.; Authors - Rune A A ; KD Validated
human	WB, IF	Ann Clin Biochem; Sucrose non-fermenting AMPK related kinase/Pentraxin 3 and DNA damage axis: a gateway to cardiovascular disease in systemic lupus erythematosus among Egyptian patients.; Authors - Doaa Hussein Zineldeen