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NUDT18 Polyklonaler Antikörper

NUDT18 Polyklonal Antikörper für IF/ICC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17318-1-PBS

Synonyme

MTH3, Nucleoside diphosphate-linked moiety X motif 18, EC:3.6.1.58, 8-oxo-dGDP phosphatase NUDT18, 7,8-dihydro-8-oxoguanine phosphatase

Filter:
  • Immunoprecipitation (IP) experiment of THP-1 cells using NUDT18 Polyclonal antibody (17318-1-AP)

    IP experiment of THP-1 using 17318-1-AP (same clone as 17318-1-PBS)

    IP result of anti-NUDT18 (IP:17318-1-AP, 4ug; Detection:17318-1-AP 1:500) with THP-1 cells lysate 2480 ug. This data was developed using the same antibody clone with 17318-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of THP-1 cells using NUDT18 Polyclonal antibody (17318-1-AP)

    IF Staining of THP-1 using 17318-1-AP (same clone as 17318-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using NUDT18 antibody (17318-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 17318-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17318-1-PBS bindet in IF/ICC, IP, Indirect ELISA NUDT18 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen NUDT18 fusion protein Ag11292
Vollständiger Name nudix (nucleoside diphosphate linked moiety X)-type motif 18
Berechnetes Molekulargewicht 323 aa, 36 kDa
Beobachtetes Molekulargewicht36 kDa
GenBank-ZugangsnummerBC016902
Gene symbol NUDT18
Gene ID (NCBI) 79873
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

8-oxo-dGDP phosphatase NUDT18, also known as MTH3, belongs to the Nudix hydrolase family that eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of various nucleotide substrates, cofactors, and signaling molecules (PMID: 35732208, 22556419). NUDT18 is specifically active against 8-oxo-dGDP and hardly cleaves 8-oxo-dGTP. NUDT18 is markedly elevated expression in noncancerous cell lines in comparison to cancerous counterpart, and NUDT18 deficient cells have been reported to exhibit a noticeably reduced proliferation rate (PMID: 38944687).