NUMBL Monoklonaler Antikörper

NUMBL Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human und mehr (1)

Anwendung

WB, IP, ELISA

Konjugation

Unkonjugiert

Publikationen(15)

CloneNo.

4C10C5

Rezensionen (1)

Kat-Nr. : 60009-1-Ig

Synonyme

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• 

  WB analysis of HepG2 using 60009-1-Ig

  HepG2 cells were subjected to SDS PAGE followed by western blot with 60009-1-Ig (NUMBL antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HepG2-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 10 publications below
• IP: See 1 publications below

Produktinformation

60009-1-Ig bindet in WB, IP, ELISA NUMBL und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: NUMBL fusion protein Ag0156
• Vollständiger Name: numb homolog (Drosophila)-like
• Berechnetes Molekulargewicht: 65 kDa
• GenBank-Zugangsnummer: BC001794
• Gene symbol: NUMBL
• Gene ID (NCBI): 9253
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Caprylsäure- Ammoniumsulfat-Präzipitation
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Numb-like (Numbl or Nbl) binds Notch and is an intracellular modulator of Notch signaling pathway. Numbl contains a phosphotyrosine binding (PTB) domain that could bind the Y682 motif present in the cytoplasmic tail of APP. Deduced molecular weight of Numbl is 72 kDa.

Publikationen

Species	Application	Title
		Elife; Host-derived Lactobacillus plantarum alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides; Authors - Yang Fu
		Elife; Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.; Authors - Li Fan
Mouse	WB	Commun Biol; STAT1 mediates the pro-inflammatory role of GBP5 in colitis; Authors - Yichen Li
	WB	Cells; PBRM1 Cooperates with YTHDF2 to Control HIF-1α Protein Translation.; Authors - Alena Shmakova
	WB	Oncol Lett; DNMT3B regulates proliferation of A549 cells through the microRNA-152-3p/NCAM1 pathway.; Authors - Bo Yang
human	WB	J Oncol; Plumbagin Enhances the Radiosensitivity of Tongue Squamous Cell Carcinoma Cells via Downregulating ATM.; Authors - Shu-Ting Pan

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.

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FH

Aleksandr (Verified Customer) (01-13-2023)

Second band was found in some samples.

• Applications: Western Blot
• Primary Antibody Dilution: 1:5000
• Cell Tissue Type: Drosophila ovaries

NUMBL Antibody Western Blot validation (1:5000 dilution) in Drosophila ovaries (Cat no:60009-1-Ig)