NUMBL Monoklonaler Antikörper

NUMBL Monoklonal Antikörper für WB,ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen

2

CloneNo.

4C10C5

Rezensionen (1)

Kat-Nr. : 60009-1-Ig

Synonyme

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Galerie der Validierungsdaten

• 

  WB analysis of HepG2 using 60009-1-Ig

  HepG2 cells were subjected to SDS PAGE followed by western blot with 60009-1-Ig (NUMBL antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HepG2-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 2 publications below

Produktinformation

60009-1-Ig bindet in WB, ELISA NUMBL und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: NUMBL fusion protein Ag0156
• Vollständiger Name: numb homolog (Drosophila)-like
• Berechnetes Molekulargewicht: 65 kDa
• GenBank-Zugangsnummer: BC001794
• Gene symbol: NUMBL
• Gene ID (NCBI): 9253
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Caprylsäure/Ammoniumsulfat-Präzipitation
• Lagerungspuffer: PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Numb-like (Numbl or Nbl) binds Notch and is an intracellular modulator of Notch signaling pathway. Numbl contains a phosphotyrosine binding (PTB) domain that could bind the Y682 motif present in the cytoplasmic tail of APP. Deduced molecular weight of Numbl is 72 kDa.

Publikationen

Species	Application	Title
human	WB	J Oncol; Plumbagin Enhances the Radiosensitivity of Tongue Squamous Cell Carcinoma Cells via Downregulating ATM.; Authors - Shu-Ting Pan
human	WB	J Transl Med; Irradiation-induced exosomal HMGB1 to confer radioresistance via the PI3K/AKT/FOXO3A signaling pathway in ESCC; Authors - Xingyu Du

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.

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FH

Aleksandr (Verified Customer) (01-13-2023)

Second band was found in some samples.

• Applications: Western Blot
• Primary Antibody Dilution: 1:5000
• Cell Tissue Type: Drosophila ovaries

NUMBL Antibody Western Blot validation (1:5000 dilution) in Drosophila ovaries (Cat no:60009-1-Ig)