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NUPL2 Polyklonaler Antikörper

NUPL2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16587-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of HEK-293 cells using NUPL2 Polyclonal antibody (16587-1-AP)

    WB analysis of HEK-293 using 16587-1-AP (same clone as 16587-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 16587-1-AP (NUPL2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16587-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human liver tissue using NUPL2 Polyclonal antibody (16587-1-AP)

    WB analysis of human liver using 16587-1-AP (same clone as 16587-1-PBS)

    human liver tissue were subjected to SDS PAGE followed by western blot with 16587-1-AP (NUPL2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16587-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of L02 cells using NUPL2 Polyclonal antibody (16587-1-AP)

    WB analysis of L02 using 16587-1-AP (same clone as 16587-1-PBS)

    L02 cells were subjected to SDS PAGE followed by western blot with 16587-1-AP (NUPL2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16587-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

16587-1-PBS bindet in WB, Indirect ELISA NUPL2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen NUPL2 fusion protein Ag8816
Vollständiger Name nucleoporin like 2
Berechnetes Molekulargewicht 45 kDa
Beobachtetes Molekulargewicht 45 kDa, 33-36 kDa
GenBank-ZugangsnummerBC005327
Gene symbol NUPL2
Gene ID (NCBI) 11097
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NUPL2 (also known as NLP-1, or hCG1) is an ubiquitous nuclear protein containing many phenylalanine-glycine (FG) repeats. As the functional orthologue of the budding yeast Nup42/Rip1 nucleoporin, NUPL2 is required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm (PMID: 10610322). In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope (PMID: 16000379). NUPL2 localizes to the nuclear envelope and could also be mobile within the nucleus. It promotes CRM1-dependent nuclear protein export (PMID: 22250199).