Nogo B receptor Polyklonaler Antikörper

Nogo B receptor Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

Kat-Nr. : 15986-1-AP

Synonyme

C6orf68, NgBR, Nogo B receptor, NUS1

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  WB analysis of mouse brain using 15986-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 15986-1-AP (NUS1 Antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse pancreas using 15986-1-AP

  mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 15986-1-AP (NUS1 antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maushirngewebe, Maus-Pankreasgewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below

Produktinformation

15986-1-AP bindet in WB, ELISA Nogo B receptor und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Nogo B receptor fusion protein Ag8789
• Vollständiger Name: nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
• Berechnetes Molekulargewicht: 293 aa, 33 kDa
• Beobachtetes Molekulargewicht: 30-33 kDa
• GenBank-Zugangsnummer: BC013026
• Gene symbol: Nogo B receptor
• Gene ID (NCBI): 116150
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Nogo proteins containing three isoforms (Nogo A, B, C) have been implicated in a variety of critical cellular processes including CNS neuronal regeneration, vascular cell spreading and chemotaxis. While only two functional receptors have been reported so far: NgR binding all three Nogos and NgBR specifically binding Nogo-B. Nogo-B receptor, also known as NgBR or NUS1, specifically binds the amino amino terminus (residues 1-200) of Nogo-B, the interaction of which is essential for stimulating chemotaxis, morphogenesis and angiogenesis.Western blot analysis detected high NgBR expression in mouse heart, liver, kidney, and pancreas with molecular weight around 30-33 kDa.

Publikationen

Species	Application	Title
mouse	WB	Front Cell Neurosci; Schwann Cell Expressed Nogo-B Modulates Axonal Branching of Adult Sensory Neurons Through the Nogo-B Receptor NgBR.; Authors - Christoph Eckharter