Napsin A Rekombinanter Antikörper
Napsin A Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
242433D1
Kat-Nr. : 86052-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
86052-1-PBS bindet in WB, Indirect ELISA Napsin A und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | Napsin A fusion protein Ag9721 |
| Vollständiger Name | napsin A aspartic peptidase |
| Berechnetes Molekulargewicht | 420 aa, 45 kDa |
| Beobachtetes Molekulargewicht | 40-45 kDa |
| GenBank-Zugangsnummer | BC017842 |
| Gene symbol | Napsin A |
| Gene ID (NCBI) | 9476 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).

