Napsin A Rekombinanter Antikörper

Napsin A Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242433D1

Kat-Nr. : 86052-1-PBS

Synonyme

NAPSA, Asp 4, ASP4, Aspartyl protease 4, EC:3.4.23.-



Geprüfte Anwendungen

Produktinformation

86052-1-PBS bindet in WB, Indirect ELISA Napsin A und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Napsin A fusion protein Ag9721
Vollständiger Name napsin A aspartic peptidase
Berechnetes Molekulargewicht 420 aa, 45 kDa
Beobachtetes Molekulargewicht 40-45 kDa
GenBank-ZugangsnummerBC017842
Gene symbol Napsin A
Gene ID (NCBI) 9476
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).