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- KD/KO Validated
Neuropilin 1/CD304 Monoklonaler Antikörper
Neuropilin 1/CD304 Monoklonal Antikörper für WB, IF/ICC, Cytometric bead array, Indirect ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
Hausschwein, human, Kaninchen
Anwendung
WB, IF/ICC, Cytometric bead array, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
2H3F6
Kat-Nr. : 60067-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
60067-1-PBS bindet in WB, IF/ICC, Cytometric bead array, Indirect ELISA Neuropilin 1/CD304 und zeigt Reaktivität mit Hausschwein, human, Kaninchen
| Getestete Reaktivität | Hausschwein, human, Kaninchen | 
| Wirt / Isotyp | Maus / IgG1 | 
| Klonalität | Monoklonal | 
| Typ | Antikörper | 
| Immunogen | Neuropilin 1/CD304 fusion protein Ag0931 | 
| Vollständiger Name | neuropilin 1 | 
| Berechnetes Molekulargewicht | 103 kDa | 
| Beobachtetes Molekulargewicht | 130 kDa | 
| GenBank-Zugangsnummer | BC007737 | 
| Gene symbol | Neuropilin 1 | 
| Gene ID (NCBI) | 8829 | 
| Konjugation | Unkonjugiert | 
| Form | Liquid | 
| Reinigungsmethode | Protein-A-Reinigung | 
| Lagerungspuffer | PBS only | 
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. | 
Hintergrundinformationen
Neuropilin-1 (NRP1) is a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.























