Neuropilin 1/CD304 Rekombinanter Antikörper

Neuropilin 1/CD304 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241812B11

Kat-Nr. : 98210-1-PBS

Synonyme

neuropilin 1, NRP1, Neuropilin-1, CD304, BDCA4

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  FC experiment of HUVEC using 98210-1-RR (same clone as 98210-1-PBS)

  1x10^6 HUVEC cells (left) or MCF-7 cells (right) were surface stained with 0.25 ug Anti-Human Neuropilin 1/CD304 Rabbit Recombinant Antibody (98210-1-RR, Clone: 241812B11) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98210-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98210-1-PBS bindet in FC Neuropilin 1/CD304 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: neuropilin 1
• GenBank-Zugangsnummer: BC007533
• Gene symbol: Neuropilin 1
• Gene ID (NCBI): 8829
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Neuropilin 1 (NRP1), also known as CD304 or VEGF165R, is a type I transmembrane proteins consisting of a small intracellular cytoplasmic domain, a transmembrane domain and an extracellular domain containing a complement-binding CUB domain (a1/a2), a coagulation factor V/VIII (b1/b2) domain, and a meprin or MAM domain (PMID: 24263240; 11886873). It is expressed on plasmacytoid dendritic cells (pDCs), endothelial cells, thymocytes, regulatory T cells, a subset of T follicular helper cells, neurons, and diverse human solid tumors (PMID: 31944572; 14991591; 18704117). Neuropilin 1 is involved in immunity, cardiovascular development, neuronal guidance, cell migration, angiogenesis and cancer pathogenesis (PMID: 24263240).