NeutraControl IL-27 Monoklonaler Antikörper
NeutraControl IL-27 Monoklonal Antikörper für ELISA, Non-Neutralization
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human
Anwendung
ELISA, Non-Neutralization
Konjugation
Unkonjugiert
CloneNo.
2F8E2
Kat-Nr. : 69534-1-Ig
Synonyme
Produktinformation
69534-1-Ig bindet in ELISA, Non-Neutralization IL-27 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG2a |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | human Humankine IL-27 protein HZ-1275 |
Vollständiger Name | interleukin 27 |
Gene symbol | IL-27 |
Gene ID (NCBI) | 246778 |
Konjugation | Unkonjugiert |
Form | Lyophilized Powder |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | Sterile PBS |
Endotoxin | <0.1 EU/μg |
Wiederherstellung | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
Stability and Storage | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
Hintergrundinformationen
IL-27 is a heterodimeric cytokine composed of two subunits: IL-27a and IL-27b. IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases.
This antibody is a neutralizing control antibody for IL-27, the immunogen is the same as Neutrakine 69034-1-Ig but could not neutralize human IL-27.