NeutraControl IL-27 Monoklonaler Antikörper

NeutraControl IL-27 Monoklonal Antikörper für ELISA, Non-Neutralization

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

ELISA, Non-Neutralization

Konjugation

Unkonjugiert

CloneNo.

2F8E2

Kat-Nr. : 69534-1-Ig

Synonyme

IL 27, IL 27 A, IL 27 subunit alpha, IL 27A, IL27, IL27 A, IL27A, IL27p28, IL30, interleukin 27, Interleukin 27 subunit alpha, p28



Produktinformation

69534-1-Ig bindet in ELISA, Non-Neutralization IL-27 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen human Humankine IL-27 protein HZ-1275
Vollständiger Name interleukin 27
Gene symbol IL-27
Gene ID (NCBI) 246778
Konjugation Unkonjugiert
Form Lyophilized Powder
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer Sterile PBS
Endotoxin<0.1 EU/μg
WiederherstellungThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Hintergrundinformationen

IL-27 is a heterodimeric cytokine composed of two subunits: IL-27a and IL-27b. IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases.

This antibody is a neutralizing control antibody for IL-27, the immunogen is the same as Neutrakine 69034-1-Ig but could not neutralize human IL-27.