OAS2 Rekombinanter Antikörper

OAS2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242801F11

Kat-Nr. : 82758-2-PBS

Synonyme

EC:2.7.7.84, 2'-5'-oligoadenylate synthase 2, 2-5A synthase 2, 242801F11, (2-5')oligo(A) synthase 2

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  WB analysis using 82758-2-RR (same clone as 82758-2-PBS)

  IFN alpha treated A549 cells were subjected to SDS PAGE followed by western blot with 82758-2-RR (OAS2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82758-2-PBS in a different storage buffer formulation.

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  WB analysis using 82758-2-RR (same clone as 82758-2-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 82758-2-RR (OAS2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82758-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

82758-2-PBS bindet in WB, Indirect ELISA OAS2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: OAS2 fusion protein Ag6170
• Vollständiger Name: 2'-5'-oligoadenylate synthetase 2, 69/71kDa
• Berechnetes Molekulargewicht: 82 kDa
• Beobachtetes Molekulargewicht: 66-71 kDa
• GenBank-Zugangsnummer: BC049215
• Gene symbol: OAS2
• Gene ID (NCBI): 4939
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The 2-prime,5-prime oligoadenylate synthetases (OASs), such as OAS2, are IFN-induced proteins characterized by their capacity to catalyze the synthesis of 2-prime,5-prime oligomers of adenosine (2-5As). OAS2 is also named as p69 OAS / p71 OAS. It has 3 isoforms(71/69/20 kDa) produced by alternative splicing. The OAS2 isozymes are 69-71 kDa and form dimers(PMID:17765707). Glycosylation is essential for its activity(PMID:9880569). Constitutive expression of the 69-kDa form of the OAS2 protein in human cells inhibited the replication of encephalomyocarditis virus (EMCV) but not that of VSV, Sendai virus, or reovirus(PMID:16501108).