OIT3 Polyklonaler Antikörper

OIT3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32301-1-PBS

Synonyme

Liver-specific zona pellucida domain-containing protein, LZP, Oncoprotein-induced transcript 3 protein, UNQ826/PRO1753

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  WB analysis using 32301-1-AP (same clone as 32301-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32301-1-AP (OIT3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32301-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

32301-1-PBS bindet in WB, Indirect ELISA OIT3 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: OIT3 fusion protein Ag36932
• Vollständiger Name: oncoprotein induced transcript 3
• Berechnetes Molekulargewicht: 60 kDa，545aa
• Beobachtetes Molekulargewicht: 70 kDa
• GenBank-Zugangsnummer: NM_152635.2
• Gene symbol: OIT3
• Gene ID (NCBI): 170392
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Oncoprotein-induced transcript 3 protein (OIT3) is a liver-specific protein. It is involved in various biological processes, including lipid metabolism and ferroptosis regulation. OIT3 has been shown to mediate macrophage polarization and facilitate hepatocellular carcinoma (HCC) progression by regulating the arachidonic acid metabolism and reactive oxygen species (ROS) accumulation (PMID: 35353239). Additionally, OIT3 is implicated in the regulation of lipid metabolism, particularly in the context of triacylglycerol and very low-density lipoproteins (VLDLs) in the liver (PMID: 36132142).