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OLIG2 Monoklonaler Antikörper

OLIG2 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

1E8C5

Kat-Nr. : 66513-1-PBS

Synonyme

OLIG2 (for WB only), 1E8C5, 5O7, bHLHb1, bHLHe19

Filter:
  • Western Blot (WB) analysis of human brain tissue using OLIG2 (for WB only) Monoclonal antibody (66513-1-Ig)

    WB analysis of human brain using 66513-1-Ig (same clone as 66513-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 66513-1-Ig (OLIG2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66513-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human cerebellum tissue using OLIG2 (for WB only) Monoclonal antibody (66513-1-Ig)

    WB analysis of human cerebellum using 66513-1-Ig (same clone as 66513-1-PBS)

    human cerebellum tissue were subjected to SDS PAGE followed by western blot with 66513-1-Ig (OLIG2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66513-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66513-1-PBS bindet in WB, ELISA OLIG2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen OLIG2 fusion protein Ag18838
Vollständiger Name oligodendrocyte lineage transcription factor 2
Berechnetes Molekulargewicht 32 kDa
Beobachtetes Molekulargewicht 35-39 kDa
GenBank-ZugangsnummerBC047511
Gene symbol OLIG2
Gene ID (NCBI) 10215
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

OLIG2, also named as BHLHB1, BHLHE19, PRKCBP2 and RACK17, is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1, OLIG2 establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. OLIG2 is widely expressed in subsets of glia cells and progenitors, and it is strongly induced at different sites by both acute and chronic injury, albeit with different mechanisms. OLIG2 acts as a repressor of neurogenesis in cells reacting to brain injury. It may represent an effective approach towards evoking neuronal repair from parenchymal precursors.(PMID:19390819 )