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OLIG2 Rekombinanter Antikörper

OLIG2 Rekombinant Antikörper für WB, IF-P, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240839C1

Kat-Nr. : 82806-7-PBS

Synonyme

240839C1, 5O7, bHLHb1, bHLHe19, Class B basic helix-loop-helix protein 1

Filter:
  • Western Blot (WB) analysis of various lysates using OLIG2 Recombinant antibody (82806-7-RR)

    WB analysis using 82806-7-RR (same clone as 82806-7-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82806-7-RR (OLIG2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82806-7-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse brain tissue using OLIG2 Recombinant antibody (82806-7-RR)

    IF Staining of mouse brain using 82806-7-RR (same clone as 82806-7-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using OLIG2 antibody (82806-7-RR, Clone: 240839C1 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 82806-7-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82806-7-RR

    Affinity and Kinetic Characterization of 82806-7-RR

    Biolayer interferometry (BLl) kinetic assays of 82806-7-RR against Human OLIG2 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

82806-7-PBS bindet in WB, IF-P, Indirect ELISA OLIG2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen OLIG2 fusion protein Ag5089
Vollständiger Name oligodendrocyte lineage transcription factor 2
Berechnetes Molekulargewicht 32 kDa
Beobachtetes Molekulargewicht35 kDa
GenBank-ZugangsnummerBC047511
Gene symbol OLIG2
Gene ID (NCBI) 10215
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

OLIG2, also named as BHLHB1, BHLHE19, PRKCBP2 and RACK17, is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1, OLIG2 establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. OLIG2 is widely expressed in subsets of glia cells and progenitors, and it is strongly induced at different sites by both acute and chronic injury, albeit with different mechanisms. OLIG2 acts as a repressor of neurogenesis in cells reacting to brain injury. It may represent an effective approach towards evoking neuronal repair from parenchymal precursors.(PMID:19390819 )