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OPN4 Polyklonaler Antikörper

OPN4 Polyklonal Antikörper für IF-P, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IF-P, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24478-1-PBS

Synonyme

Filter:
  • Immunofluorescence (IF) / fluorescent staining of mouse eye tissue using OPN4 Polyclonal antibody (24478-1-AP)

    IF Staining of mouse eye using 24478-1-AP (same clone as 24478-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse eye tissue using OPN4 antibody (24478-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 24478-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

24478-1-PBS bindet in IF-P, Indirect ELISA OPN4 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen OPN4 fusion protein Ag21643
Vollständiger Name opsin 4
Berechnetes Molekulargewicht 478 aa, 53 kDa
GenBank-ZugangsnummerBC113558
Gene symbol OPN4
Gene ID (NCBI) 94233
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

OPN4, an opsin that was first isolated from the skin of Xenopus laevis in 1998, belongs not to the vertebrate-type opsin family but rather to the invertebrate-type opsins, which are part of the seven-transmembrane G protein-coupled receptor (GPCR) family (PMID:31989708). In humans, OPN4 is expressed in the retinal ganglion cells in addition to part of the brain (PMID:10632589). Moreover, Opn4 functions as a photoreceptor by detecting brightness levels and discriminating visual signals (PMID:22633808). Opn4 also facilitates visual circuits to acquire optimal settings and light adaptation by measuring irradiance levels (PMID:25517373).