OPRM1 Polyklonaler Antikörper

OPRM1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27625-1-PBS

Synonyme

MOR, MOP, M OR 1, LMOR, KIAA0403

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  WB analysis using 27625-1-AP (same clone as 27625-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27625-1-AP (OPRM1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27625-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 27625-1-AP (same clone as 27625-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 27625-1-AP (OPRM1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27625-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 27625-1-AP (same clone as 27625-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 27625-1-AP (OPRM1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27625-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

27625-1-PBS bindet in WB, IHC, Indirect ELISA OPRM1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: OPRM1 fusion protein Ag24806
• Vollständiger Name: opioid receptor, mu 1
• Berechnetes Molekulargewicht: 45 kDa
• Beobachtetes Molekulargewicht: 65-70 kDa
• GenBank-Zugangsnummer: BC074927
• Gene symbol: OPRM1
• Gene ID (NCBI): 4988
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

OPRM1 (also known as Mu opioid receptor, MOR1, MOP) is a G protein-coupled receptor that mediates the physiological effects of endogenous opioids as well as the structurally distinct opioid alkaloids including morphine and etorphine (PMID: 9618555). Mu opioid receptor modulates a wide range of physiological functions, particularly involved in the control of pain perception and reward properties (PMID: 30483121). Mu opioid receptor is the principal target of opioid drugs. It is encoded by OPRM1 gene and multiple transcript variants encoding different isoforms have been found. Mu opioid receptor contains sites for N-linked glycosylation. The transcript variants and variations of glycosylation may result in migrating bands of Mu opioid receptor (PMID: 21886594; 11359768).