ORAI1 Monoklonaler Antikörper

ORAI1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3C12F9

Kat-Nr. : 66223-1-PBS

Synonyme

ORAI1-L2, Orail-L2, 3C12F9, Calcium release-activated calcium channel protein 1, CRACM1

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  WB analysis using 66223-1-Ig (same clone as 66223-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66223-1-Ig (ORAI1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66223-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 66223-1-Ig (same clone as 66223-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66223-1-Ig (ORAI1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66223-1-PBS in a different storage buffer formulation.

• 

  WB analysis of A375 using 66223-1-Ig (same clone as 66223-1-PBS)

  A375 cells were subjected to SDS PAGE followed by western blot with 66223-1-Ig (ORAI1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66223-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66223-1-PBS bindet in WB, Indirect ELISA ORAI1 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

• Getestete Reaktivität: Hausschwein, human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: ORAI1 fusion protein Ag18050
• Vollständiger Name: ORAI calcium release-activated calcium modulator 1
• Berechnetes Molekulargewicht: 301 aa, 33 kDa
• Beobachtetes Molekulargewicht: 32 kDa
• GenBank-Zugangsnummer: BC015369
• Gene symbol: ORAI1
• Gene ID (NCBI): 84876
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a 32-55 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combinaed immunodeficiency (SCID) syndrome possess point mutations in Orai1 gene.