ORAOV1 Polyklonaler Antikörper
ORAOV1 Polyklonal Antikörper für IP, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
IP, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 32706-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
32706-1-PBS bindet in IP, Indirect ELISA ORAOV1 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | ORAOV1 fusion protein Ag38523 |
| Vollständiger Name | oral cancer overexpressed 1 |
| Berechnetes Molekulargewicht | 15kDa,137aa |
| Beobachtetes Molekulargewicht | 16 kDa |
| GenBank-Zugangsnummer | NM_153451.2 |
| Gene symbol | ORAOV1 |
| Gene ID (NCBI) | 220064 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
ORAOV1 (oral cancer overexpressed 1) is a candidate proto-oncogene that is frequently amplified and overexpressed in various human squamous cell carcinomas (SCCs), including oral, esophageal, and cervical cancers. In cervical cancer, silencing of ORAOV1 significantly inhibits the growth of HeLa cells by causing S-phase cell cycle arrest and activating apoptosis. Additionally, ORAOV1 is overexpressed in a variety of solid tumors and may promote tumor development by preventing ribosomal damage induced by reactive oxygen species (ROS). Therefore, ORAOV1 is not only an important tumor biomarker but also a potential therapeutic target for multiple cancers.

