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OSCAR Polyklonaler Antikörper

OSCAR Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21996-1-PBS

Synonyme

Poly-Ig receptor 3, PIgR-3, PIgR3, Osteoclast-associated receptor, Osteoclast-associated immunoglobulin-like receptor

Filter:
  • Western Blot (WB) analysis of various lysates using OSCAR Polyclonal antibody (21996-1-AP)

    WB analysis using 21996-1-AP (same clone as 21996-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21996-1-AP (OSCAR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21996-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

21996-1-PBS bindet in WB, Indirect ELISA OSCAR und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen OSCAR fusion protein Ag17366
Vollständiger Name osteoclast associated, immunoglobulin-like receptor
Berechnetes Molekulargewicht 282 aa, 31 kDa
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerBC035023
Gene symbol OSCAR
Gene ID (NCBI) 126014
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Osteoclast-associated receptor (OSCAR) is an FcRγ-associated receptor that belongs to the leukocyte receptor cluster (LRC). OSCAR is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells(PMID: 15155468; PMID: 15650060). OSCAR is expressed in osteoclast cells and involved in the differentiation of osteoclasts from peripheral blood mononuclear cells (PBMC). The N-glycosylated form of human OSCAR has a molecular weight of approximately 40-45 kDa, while 30 kDa corresponds to its fully non-glycosylated form (PMID: 15155468; 24902903; 27917924)