OSGIN1 Polyklonaler Antikörper

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• KD/KO Validated

OSGIN1 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IP, ELISA

Konjugation

Unkonjugiert

Publikationen(7)

Kat-Nr. : 15248-1-AP

Synonyme

BDGI, BMSC-derived growth inhibitor, Bone marrow stromal cell-derived growth inhibitor, huOKL38, OKL38

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  WB analysis using 15248-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 15248-1-AP (OSGIN1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 15248-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 15248-1-AP (OSGIN1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: A549-Zellen, Mauslebergewebe, Maus-Eierstockgewebe, Ratten-Eierstockgewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 7 publications below
• IHC: See 1 publications below
• IP: See 1 publications below

Produktinformation

15248-1-AP bindet in WB, IHC, IP, ELISA OSGIN1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: OSGIN1 fusion protein Ag4295
• Vollständiger Name: oxidative stress induced growth inhibitor 1
• Berechnetes Molekulargewicht: 61 kDa
• Beobachtetes Molekulargewicht: 52 kDa
• GenBank-Zugangsnummer: BC032476
• Gene symbol: OSGIN1
• Gene ID (NCBI): 29948
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

OSGIN1, also named as BDGI and OKL38, belongs to the OKL38 family. OSGIN1 is a gene linked to oxidative stress and cell death in other tissues, was markedly upregulated in smokers compared to nonsmokers (PMID: 28548877). OSGIN1 has 3 isoforms with the molecular mass of 38, 52 and 61 kDa (PMID: 28181536).

Publikationen

Species	Application	Title
human	WB	J Hazard Mater; METTL3 regulates PM2.5-induced cell injury by targeting OSGIN1 in human airway epithelial cells.; Authors - Qi Yuan
human	WB,IP,IHC	Cell Mol Life Sci; OSGIN1 is a novel TUBB3 regulator that promotes tumor progression and gefitinib resistance in non-small cell lung cancer; Authors - Xiaomeng Xie
human	WB	Toxicol Lett; LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.; Authors - Ming Gao ; KD Validated
human	WB	J Pharmacol Exp Ther; Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress.; Authors - Ramon Martinez
human	WB	Toxicol Lett; OSGIN1 regulates PM2.5-induced fibrosis via mediating autophagy in an in vitro model of COPD; Authors - Xiying Tang
mouse	WB	Int J Mol Sci; Methylmercury Induces Apoptosis in Mouse C17.2 Neural Stem Cells through the Induction of OSGIN1 Expression by NRF2; Authors - Naoya Yamashita