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OSMR Monoklonaler Antikörper

OSMR Monoklonal Antikörper für ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

ELISA

Konjugation

Unkonjugiert

CloneNo.

4B11D4

Kat-Nr. : 60071-1-Ig

Synonyme

Galerie der Validierungsdaten

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  • Western Blot (WB) analysis of human brain tissue using OSMR Monoclonal antibody (60071-1-Ig)

    WB analysis of human brain using 60071-1-Ig

    human brain tissue were subjected to SDS PAGE followed by western blot with 60071-1-Ig (OSMR antibody) at dilution of 1:250 incubated at room temperature for 1.5 hours.

Geprüfte Anwendungen

Empfohlene Verdünnung

AnwendungVerdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

60071-1-Ig bindet in ELISA OSMR und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen OSMR fusion protein Ag1426
Vollständiger Name oncostatin M receptor
Berechnetes Molekulargewicht 110 kDa
Beobachtetes Molekulargewicht 120 kDa
GenBank-ZugangsnummerBC010943
Gene symbol OSMR
Gene ID (NCBI) 9180
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Oncostatin M (OSM) is a member of interleukin-6 family cytokines that modulates proliferation and differentiation in numerous cells (PMID: 22982441). OSM signals via a receptor complex comprising gp130 and the OSMR (also refered to as OSMRβ) (PMID: 8999038). OSMR is a single-pass membrane protein which belongs to the type I cytokine receptor family. OSMR mRNA is expressed at relatively high levels in all neural cells as well as fibroblast, epithelial and a variety of tumor cell lines (PMID: 8999038). It has also been shown that OSMR associates with IL31RA to form the heterodimeric IL31 receptor (PMID: 15184896).