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OSTA Polyklonaler Antikörper

OSTA Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31330-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using OSTA Polyclonal antibody (31330-1-AP)

    WB analysis using 31330-1-AP (same clone as 31330-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31330-1-AP (SLC51A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31330-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31330-1-PBS bindet in WB, Indirect ELISA OSTA und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen OSTA fusion protein Ag34517
Vollständiger Name organic solute transporter alpha
Berechnetes Molekulargewicht340 aa, 38 kDa
Beobachtetes Molekulargewicht 38 kDa
GenBank-ZugangsnummerNM_152672
Gene symbol SLC51A
Gene ID (NCBI) 200931
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC51A also known as OSTA, belongs to the OST-alpha family. SLC51A is an essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood (PubMed:16317684). SLC51A is located in basolateral plasma membrane and transported from the endoplasmic reticulum to the plasma membrane upon interacting with SLC51B. SLC51A is expressed with a high expression in kidney and intestine (PMID: 15563450). Mutations in SLC51A are associated with Cholestasis progressive familial intrahepatic 6(PMID: 31863603).