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OSTbeta / SLC51B Polyklonaler Antikörper

OSTbeta / SLC51B Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21248-1-PBS

Synonyme

Filter:
  • Immunohistochemistry (IHC) staining of human small intestine tissue using OSTbeta / SLC51B Polyclonal antibody (21248-1-AP)

    IHC staining of human small intestine using 21248-1-AP (same clone as 21248-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 21248-1-AP (OSTbeta antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 21248-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human small intestine tissue using OSTbeta / SLC51B Polyclonal antibody (21248-1-AP)

    IHC staining of human small intestine using 21248-1-AP (same clone as 21248-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 21248-1-AP (OSTbeta antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 21248-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

21248-1-PBS bindet in IHC, Indirect ELISA OSTbeta / SLC51B und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen OSTbeta / SLC51B fusion protein Ag15751
Vollständiger Name organic solute transporter beta
Berechnetes Molekulargewicht 128 aa, 14 kDa
GenBank-ZugangsnummerBC103842
Gene symbol SLC51B
Gene ID (NCBI) 123264
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Organic solute transporter alpha-beta (Ostα-Ostβ) is a heteromeric transporter that has been localized to the basolateral membrane of epithelial cells of the small intestine, kidney and liver, and appears to be essential for bile acid homeostasis. The transporter is composed of a predicted 340-amino acid, 7-transmembrane domain protein (Ostα) and a putative 128-amino acid, single-transmembrane domain polypeptide (Ostβ). Ostα-Ostβ transports bile acids by a facilitated diffusion mechanism; therefore, Ostα-Ostβ can mediate cellular efflux or uptake depending on the substrate's electrochemical gradient. It's reported that Ostα-Ostβ is not only essential for bile acid, but also vital for sterol disposition and enterohepatic circulation(PMID: 21691099).