OTUD7B Monoklonaler Antikörper

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• KD/KO Validated

OTUD7B Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2C12D9

Kat-Nr. : 66276-1-PBS

Synonyme

CEZANNE, OTU domain containing 7B, OTUD7B, ZA20D1, Zinc finger protein Cezanne

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  WB analysis of Jurkat using 66276-1-Ig (same clone as 66276-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 66276-1-Ig (OTUD7B Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66276-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66276-1-PBS bindet in WB, Indirect ELISA OTUD7B und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: OTUD7B fusion protein Ag10513
• Vollständiger Name: OTU domain containing 7B
• Berechnetes Molekulargewicht: 427aa,48 kDa; 843aa,93 kDa
• Beobachtetes Molekulargewicht: 92 kDa
• GenBank-Zugangsnummer: BC020622
• Gene symbol: OTUD7B
• Gene ID (NCBI): 56957
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

OUTD7B is a member of the A20 family of the deubiquitinating cysteine proteases, which has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. It plays a key role in the negative feedback regulation of NF-κB signaling in response to multiple stimuli and has been described as central gatekeeper in inflammation and immunity.