OXGR1 Polyklonaler Antikörper

OXGR1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22069-1-PBS

Synonyme

2 oxoglutarate receptor 1, Alpha ketoglutarate receptor 1, G protein coupled receptor 80, G protein coupled receptor 99, GPR80

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  WB analysis using 22069-1-AP (same clone as 22069-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22069-1-AP (OXGR1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22069-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

22069-1-PBS bindet in WB, Indirect ELISA OXGR1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: OXGR1 fusion protein Ag17186
• Vollständiger Name: oxoglutarate (alpha-ketoglutarate) receptor 1
• Berechnetes Molekulargewicht: 337 aa, 38 kDa
• Beobachtetes Molekulargewicht: 38-42 kDa
• GenBank-Zugangsnummer: BC103881
• Gene symbol: OXGR1
• Gene ID (NCBI): 27199
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

2-oxoglutarate receptor 1(OXGR1) also known as GPR99, belongs to the G-protein coupled receptor family. OXGR1is expressed in renal cortical connecting tubule and collecting duct type B intercalated cells. When stimulated by its ligand, OXGR1 mediates cellular calcium uptake, which acts as a signal to promote the chloride-bicarbonate exchanger SLC26A4. Dominant loss-of-function OXGR1 variants are associated with recurrent calcium oxalate NL/NC disease(PMID: 36571463).