P-Selectin/CD62P Rekombinanter Antikörper

P-Selectin/CD62P Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

240766F5

Kat-Nr. : 98302-2-PBS

Synonyme

P-selectin, CD62P, 240766F5, PADGEM, P selectin

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  FC experiment of mouse peripheral blood platelets using 98302-2-RR (same clone as 98302-2-PBS)

  1x10^6 Thrombin treated mouse peripheral blood platelets were surface stained with 0.25 ug Anti-Mouse P-Selectin/CD62P Rabbit RecAb (98302-2-RR, Clone: 240766F5) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Untreated mouse peripheral blood platelets were surface stained with 0.25 ug Anti-Mouse P-Selectin/CD62P Rabbit RecAb (98302-2-RR, Clone: 240766F5) and PE-conjugated Goat Anti-Rabbit IgG (black, dashed). Cells were not fixed. This data was developed using the same antibody clone with 98302-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98302-2-PBS bindet in FC P-Selectin/CD62P und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: selectin, platelet
• Berechnetes Molekulargewicht: 83 kDa
• GenBank-Zugangsnummer: NM_011347.2
• Gene symbol: Selp
• Gene ID (NCBI): 20344
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.