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P2RX6 Rekombinanter Antikörper

P2RX6 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241620B10

Kat-Nr. : 84458-4-PBS

Synonyme

P2XM, P2X6, P2X purinoceptor 6, P2RXL1, ATP receptor

Filter:
  • Western Blot (WB) analysis of mouse skeletal muscle tissue using P2RX6 Recombinant antibody (84458-4-RR)

    WB analysis of mouse skeletal muscle using 84458-4-RR (same clone as 84458-4-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 84458-4-RR (P2RX6 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84458-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84458-4-RR

    Affinity and Kinetic Characterization of 84458-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84458-4-RR against Human P2RX6 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

84458-4-PBS bindet in WB, Indirect ELISA P2RX6 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen P2RX6 fusion protein Ag12331
Vollständiger Name purinergic receptor P2X, ligand-gated ion channel, 6
Berechnetes Molekulargewicht 431 aa, 48 kDa
Beobachtetes Molekulargewicht 45 kDa
GenBank-ZugangsnummerBC033488
Gene symbol P2RX6
Gene ID (NCBI) 9127
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The P2 receptors have two subfamilies in mammalian cells, P2X and P2Y. P2X family of ligand-gated ion channel receptors have seven members, P2RX1-7, which all constitute non-selective cation channels proposed to be functional under a homo- or heterotrimeric association. P2RX6 is predominantly expressed in skeletal muscle, and regulated by p53. It's reported that ATP might increase renal cell carcinoma cells migration and invasion through P2RX6.(PMID: 31159832, PMID:9242461)