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P53 Rekombinanter Antikörper
P53 Rekombinant Antikörper für WB, IHC-Autostainer, IF/ICC, FC (Intra), Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Zebrafisch
Anwendung
WB, IHC-Autostainer, IF/ICC, FC (Intra), Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
2H13
Kat-Nr. : 80077-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
80077-1-PBS bindet in WB, IHC-Autostainer, IF/ICC, FC (Intra), Indirect ELISA P53 und zeigt Reaktivität mit human, Zebrafisch
Getestete Reaktivität | human, Zebrafisch |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | Peptid |
Vollständiger Name | tumor protein p53 |
Berechnetes Molekulargewicht | 44 kDa |
Beobachtetes Molekulargewicht | 53 kDa |
GenBank-Zugangsnummer | BC003596 |
Gene symbol | P53 |
Gene ID (NCBI) | 7157 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
TP53, also known as P53 and NY-CO-13, belongs to the p53 family and has 9 isoforms. In SDS-Page, the observed molecular weight is about 53 kDa. TP53 acts as a tumor suppressor in many tumor types, including growth arrest or apoptosis depending on the physiological circumstances and cell types. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. TP53 Localizes in the nucleus in most cells but found in the cytoplasm in some cells. (PMID: 26166714; PMID: 25225161)