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P53 Rekombinanter Antikörper

P53 Rekombinant Antikörper für WB, IHC-Autostainer, IF/ICC, FC (Intra), Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Zebrafisch

Anwendung

WB, IHC-Autostainer, IF/ICC, FC (Intra), Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2H13

Kat-Nr. : 80077-1-PBS

Synonyme

TP53, 2H13, Antigen NY-CO-13, tumor protein p53, Tumor suppressor p53



Geprüfte Anwendungen

Produktinformation

80077-1-PBS bindet in WB, IHC-Autostainer, IF/ICC, FC (Intra), Indirect ELISA P53 und zeigt Reaktivität mit human, Zebrafisch

Getestete Reaktivität human, Zebrafisch
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name tumor protein p53
Berechnetes Molekulargewicht 44 kDa
Beobachtetes Molekulargewicht53 kDa
GenBank-ZugangsnummerBC003596
Gene symbol P53
Gene ID (NCBI) 7157
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TP53, also known as P53 and NY-CO-13, belongs to the p53 family and has 9 isoforms. In SDS-Page, the observed molecular weight is about 53 kDa. TP53 acts as a tumor suppressor in many tumor types, including growth arrest or apoptosis depending on the physiological circumstances and cell types. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. TP53 Localizes in the nucleus in most cells but found in the cytoplasm in some cells. (PMID: 26166714; PMID: 25225161)